Mediastinal Masses

A thorough assessment of the applications of inorganic mass spectrometry Mass spectrometry is a powerful analytical technique used to identify unknown compounds, to quantify known materials, and to elucidate the structural and chemical properties of molecules. Inorganic mass spectrometry focuses on the analysis of metals and elements rather than organic compounds. Applications of Inorganic Mass Spectrometry describes developments in mass spectrometric instrumentation, together with applications in metrology, nuclear science, cosmochemistry, geoscience, environmental science, and planetary science. Divided into two parts, the first part of the book reviews the numerous technological advances that have occurred in mass spectrometry since 1947, a date regarded as the birth of modern mass spectrometry. The second part offers an up-to-date description of the many applications of inorganic mass spectrometry and includes a comprehensive set of references for each application. It is doubtful that any other analytical instrument has had such a significant impact in so many fields of science as mass spectrometry. Applications of Inorganic Mass Spectrometry provides researchers, scientists, and engineers with an essential reference for this vital science.

A practical introduction to contemporary instrumentation, techniques, and applications This book provides professionals in the biological sciences with a solid basis in the fundamentals of contemporary mass spectrometry so that they can confidently choose and apply the best instrumentation and experimental approaches for their needs. The only single-volume guide of its kind, Principles and Practice of Biological Mass Spectrometry offers comprehensive coverage of the latest instrumentation, techniques, and applications in the rapidly expanding field of biological mass spectrometry, making it an excellent working resource for experts and novices alike. Principles and Practice of Biological Mass Spectrometry begins with a detailed review of the fundamentals of and recent developments in biological mass spectrometry instrumentation. This is followed by practical, well-illustrated instances of important mass spectrometric techniques, including: Tandem mass spectrometryCollision-induced dissociationMolecular mass determinationCoupling of mass spectrometry with separation techniquesQuantification The final portion of the book is devoted to an exploration of contemporary approaches to the characterization of the various classes of compounds relevant to the biological sciences. While the emphasis is on proteins and peptides, nucleic acid, carbohydrates, and lipids, pharmaceutical drugs and metabolites also receive extensive coverage. Throughout, coverage is generously supplemented with examples of applications across a wide range of commercial and academic venues. Principles and Practice of Biological Mass Spectrometry is an invaluable working resource for chemists, biochemists,biologists, molecular biologists, biomedical researchers, pharmacologists, immunologists, forensic scientists, environmental scientists, and all whose research involves the analysis of biological compounds.